email: fpasha@fas.harvard.edu



Estimation of ventricular fiber orientations in infarcted hearts for patient-specific simulations


Journal article


F. Vadakkumpadan, H. Arevalo, F. Pashakhanloo, Anthony Alers, F. Dawoud, K. Schuleri, D. Herzka, E. McVeigh, A. Lardo, N. Trayanova
2013 IEEE 10th International Symposium on Biomedical Imaging, 2013

Semantic Scholar DBLP DOI
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APA   Click to copy
Vadakkumpadan, F., Arevalo, H., Pashakhanloo, F., Alers, A., Dawoud, F., Schuleri, K., … Trayanova, N. (2013). Estimation of ventricular fiber orientations in infarcted hearts for patient-specific simulations. 2013 IEEE 10th International Symposium on Biomedical Imaging.


Chicago/Turabian   Click to copy
Vadakkumpadan, F., H. Arevalo, F. Pashakhanloo, Anthony Alers, F. Dawoud, K. Schuleri, D. Herzka, E. McVeigh, A. Lardo, and N. Trayanova. “Estimation of Ventricular Fiber Orientations in Infarcted Hearts for Patient-Specific Simulations.” 2013 IEEE 10th International Symposium on Biomedical Imaging (2013).


MLA   Click to copy
Vadakkumpadan, F., et al. “Estimation of Ventricular Fiber Orientations in Infarcted Hearts for Patient-Specific Simulations.” 2013 IEEE 10th International Symposium on Biomedical Imaging, 2013.


BibTeX   Click to copy

@article{f2013a,
  title = {Estimation of ventricular fiber orientations in infarcted hearts for patient-specific simulations},
  year = {2013},
  journal = {2013 IEEE 10th International Symposium on Biomedical Imaging},
  author = {Vadakkumpadan, F. and Arevalo, H. and Pashakhanloo, F. and Alers, Anthony and Dawoud, F. and Schuleri, K. and Herzka, D. and McVeigh, E. and Lardo, A. and Trayanova, N.}
}

Abstract

Patient-specific modeling of the heart is limited by lack of technology to acquire myocardial fiber orientations in the clinic. To overcome this limitation, we recently developed an image-based methodology to estimate the fiber orientations. In this study, we test the efficacy of that methodology in infarcted hearts. To this end, we implemented a processing pipeline to compare estimated fiber orientations of infarcted hearts with measured ones, and quantify the effect of the estimation error on outcomes of electrophysiological simulations. The pipeline was applied to images that we acquired from three infarcted canine hearts. The new insights obtained from the project will pave the way for the development of patient-specific models of infarcted hearts that can aid physicians in personalized diagnosis and decisions regarding electrophysiological interventions.


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